Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3808267 | 0.99 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL3817882 | 0.85 | OPRM1 (0.45) | OPRM1OPRK1CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL3815960 | 0.84 | OPRM1 (0.46) | OPRM1OPRK1CYP19A1TBXAS1 | |
| SCHEMBL47979 | 0.81 | CYP19A1 (0.43) | OPRM1OPRK1CYP19A1TBXAS1 | |
| SCHEMBL3809768 | 0.81 | CYP19A1 (0.43) | ALDH1A1KDM4EOPRM1OPRK1CYP19A1 | |
| SCHEMBL3815489 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL13873185 | 0.80 | CYP19A1 (0.46) | OPRM1OPRK1CYP19A1TBXAS1 | |
| SCHEMBL3813271 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL3817934 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| Oxalic Acid SCHEMBL3811985 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EOPRM1OPRK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |