Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346979 | 0.84 | ALDH1A1 (0.44) | SLC22A12ALDH1A1TDP1HSD11B1TSHR | |
| SCHEMBL6689411 | 0.81 | ALDH1A1 (0.40) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL13918951 | 0.81 | FFAR1 (0.41) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL313726 | 0.76 | ALDH1A1 (0.40) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL5250349 | 0.76 | FFAR1 (0.43) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL1861089 | 0.74 | ALDH1A1 (0.39) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL96903 | 0.74 | FFAR1 (0.41) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL30794742 | 0.74 | AR (0.59) | SLC22A12AR | |
| SCHEMBL103847 | 0.74 | AR (0.59) | SLC22A12AR | |
| SCHEMBL8479886 | 0.74 | ALDH1A1 (0.39) | SLC22A12ALDH1A1TDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-A1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | Bayer Pharma Aktiengesellschaft (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105770-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |