SCHEMBL381401

SCHEMBL381401

CC(C)[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP2D6 P10635 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TAAR1 Q96RJ0 5/20 0.33
SLC6A2 P23975 2/20 0.33
TSHR P16473 2/20 0.33
ALOX12 P18054 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745989 0.78 TSHR (0.38) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL380701 0.77 TAAR1 (0.39) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL8992272 0.74 TAAR1 (0.37) LMNAADRA2AADRA2CHIF1ATDP1
Fluoride SCHEMBL27639902 0.74 MAOA (0.38) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL16105241 0.74 TRPA1 (0.41) LMNAADRA2CTAAR1SLC6A2TSHR
SCHEMBL8344991 0.69 TRPA1 (0.36) LMNATDP1CYP2D6TAAR1SLC6A2
SCHEMBL1325498 0.69 DPP4 (0.39) LMNAKDM4ETDP1CYP2D6ALDH1A1
SCHEMBL27910779 0.67
SCHEMBL671215 0.65 TAAR1 (0.34) HIF1ATDP1CYP2D6ALDH1A1TAAR1
SCHEMBL3529369 0.65 MIF (0.35) LMNATDP1ALDH1A1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1028 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230258563-A1 DETECTION OF VOLATILES ISOBIONICS B V (NL) 2023-08-17 US claimed
EP-3998304-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SmartKem Limited (GB) 2022-05-18 EP claimed
EP-2817355-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-03-24 EP claimed
EP-2817356-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-02-17 EP claimed
EP-2817354-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-01-13 EP claimed
EP-2817357-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-11-04 EP claimed
EP-2817352-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-08-26 EP claimed
EP-2817351-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-08-26 EP claimed
US-10707420-B2 Polycyclic aromatic hydrocarbon copolymer-containing organic semiconductor compositions SMARTKEM LIMITED (GB) 2020-07-07 US claimed
US-10056550-B2 Polycyclic aromatic hydrocarbon copolymers and their use as organic semiconductors SMARTKEM LIMITED (GB) 2018-08-21 US claimed
EP-2817364-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS Smartkem Limited (GB) 2014-12-31 EP claimed
WO-2013124685-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124688-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124682-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124683-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124684-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124687-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124686-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed