SCHEMBL380701

SCHEMBL380701

CC(C)[Si](c1ccccc1)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.39
SLC6A2 P23975 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 1/20 0.36
DPP4 P27487 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27639902 0.97 MAOA (0.38) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL381401 0.77 LMNA (0.37) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL8992272 0.74 TAAR1 (0.37) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL28153554 0.74 TRPA1 (0.41) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL8344991 0.69 TRPA1 (0.36) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL9745989 0.67 TSHR (0.38) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL24932018 0.67 DPP4 (0.58) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL830 0.67
SCHEMBL5565016 0.67 DPP4 (0.58) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL4916236 0.67 DPP4 (0.58) TAAR1SLC6A2MAOASLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023070009-A1 SILYL ETHER DERIVATIVES OF POLYETHER POLYMERS P2 SCIENCE, INC. (US) 2023-04-27 WO claimed
EP-3998304-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SmartKem Limited (GB) 2022-05-18 EP claimed
US-11028386-B2 Morpholino oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2021-06-08 US claimed
EP-2817355-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-03-24 EP claimed
CN-106795186-B Process for preparing morpholino oligonucleotides 味之素株式会社 2021-03-02 CN claimed
EP-2817356-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-02-17 EP claimed
EP-2817354-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-01-13 EP claimed
US-10833274-B2 Organic semiconductor compositions SMARTKEM LIMITED (GB) 2020-11-10 US claimed
EP-2817357-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-11-04 EP claimed
EP-2817351-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-08-26 EP claimed
EP-2817355-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS Smartkem Limited (GB) 2014-12-31 EP claimed
EP-2817352-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS Smartkem Limited (GB) 2014-12-31 EP claimed
WO-2013124687-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124685-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124684-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124688-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124682-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124683-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124686-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028386-B2 Morpholino oligonucleotide manufacturing method DCLRE1B, RNGTT, RTCB TAAR1 4592/4885SLC6A2 4368/4885MAOA 2979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.