Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816884 | 0.92 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL3811075 | 0.89 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL3816632 | 0.89 | NPSR1 (0.49) | MEN1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL3807367 | 0.87 | NPSR1 (0.46) | ALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL3816563 | 0.87 | NPSR1 (0.54) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL3812602 | 0.87 | NPSR1 (0.46) | KDM4ENPSR1RXFP1 | |
| SCHEMBL2157723 | 0.86 | NPSR1 (0.50) | MEN1KMT2AKDM4ENPSR1RXFP1 | |
| SCHEMBL3816724 | 0.86 | ACLY (0.47) | NPSR1 | |
| SCHEMBL3815294 | 0.86 | NPSR1 (0.42) | KDM4ENPSR1RXFP1 | |
| SCHEMBL3811426 | 0.86 | RAD52 (0.47) | MEN1KMT2AHTTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |