SCHEMBL381485

SCHEMBL381485

O=P(O)(Oc1ccc(/N=N/c2ccccc2)cc1)Oc1ccc2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.49
MEN1 O00255 8/20 0.46
KMT2A Q03164 8/20 0.46
NPC1 O15118 6/20 0.46
RAB9A P51151 6/20 0.46
HSP90AA1 P07900 3/20 0.46
CETP P11597 1/20 0.45
MAPT P10636 3/20 0.41
SRC P12931 1/20 0.41
PTPN7 P35236 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 4/20 0.40
GAA P10253 1/20 0.39
TRPA1 O75762 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381486 1.00 GPR84 (0.49) GPR84MEN1KMT2ANPC1RAB9A
SCHEMBL10792972 0.87 GPR84 (0.58) GPR84MEN1KMT2ARAB9ACETP
SCHEMBL7878424 0.85 GPR84 (0.63) GPR84MEN1KMT2ANPC1RAB9A
SCHEMBL381178 0.80 GPR84 (0.43) GPR84MEN1KMT2ANPC1RAB9A
SCHEMBL381177 0.80 GPR84 (0.43) GPR84MEN1KMT2ANPC1RAB9A
SCHEMBL29181663 0.79 SRC (0.67) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL9625400 0.79 SRC (0.67) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL27753829 0.76 GPR84 (0.56) GPR84MEN1KMT2ANPC1RAB9A
SCHEMBL2344043 0.75 GPR84 (0.63) GPR84MEN1KMT2ARAB9ACETP
SCHEMBL29848582 0.75 GPR84 (0.63) GPR84MEN1KMT2ARAB9ACETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9806266-B2 Salts of phosphorus oxide as N-dopants for organic electronics SIEMENS AKTIENGESELLSCHAFT (DE) 2017-10-31 US claimed
EP-2885825-B1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS SIEMENS AG (DE) 2016-07-06 EP claimed
US-20150255719-A1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS SIEMENS AKTIENGESELLSCHAFT (DE) 2015-09-10 US claimed
EP-2885825-A1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS Siemens Aktiengesellschaft (DE) 2015-06-24 EP claimed
US-9806266-B2 Salts of phosphorus oxide as N-dopants for organic electronics SIEMENS AKTIENGESELLSCHAFT (DE) 2017-10-31 US disclosed
WO-2017095806-A1 SITE-SPECIFIC RADIOFLUORINATION OF PEPTIDES WITH 8-[18F]-FLUOROOCTANOIC ACID CATALYZED BY LIPOIC ACID LIGASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-06-08 WO disclosed
EP-2885825-B1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS SIEMENS AG (DE) 2016-07-06 EP disclosed
US-9284541-B2 Methods and compositions for protein labeling using lipoic acid ligases MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-03-15 US disclosed
US-20150255719-A1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS SIEMENS AKTIENGESELLSCHAFT (DE) 2015-09-10 US disclosed
EP-2885825-A1 SALTS OF PHOSPHORUS OXIDE AS N-DOPANTS FOR ORGANIC ELECTRONICS Siemens Aktiengesellschaft (DE) 2015-06-24 EP disclosed
US-20150125904-A1 PROBE INCORPORATION MEDIATED BY ENZYMES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-05-07 US disclosed
US-8871456-B2 Probe incorporation mediated by enzymes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-28 US disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 US disclosed
US-20090149631-A1 Methods and compositions for protein labeling using lipoic acid ligases MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-06-11 US disclosed
WO-2009064366-A2 METHODS AND COMPOSITIONS FOR PROTEIN LABELING USING LIPOIC ACID LIGASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-05-22 WO disclosed
WO-2008087031-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2008-07-24 WO disclosed
WO-2007041689-A2 METHODS OF SITE-SPECIFIC LABELING OF MOLECULES AND MOLECULES PRODUCED THEREBY PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-04-12 WO disclosed
US-7172877-B2 Methods and compositions for peptide and protein labeling MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-02-06 US disclosed
US-20050233389-A1 Methods and compositions for peptide and protein labeling MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-10-20 US disclosed
US-20040209317-A1 Methods and compositions for peptide and protein labeling MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233389-A1 Methods and compositions for peptide and protein labeling HLCS, BTD, QPCTL GPR84 3426/4885MEN1 1564/4885KMT2A 3151/4885
US-20090149631-A1 Methods and compositions for protein labeling using lipoic acid ligases HLCS, ACSL5, ACSL1 GPR84 4373/4885MEN1 2580/4885KMT2A 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.