SCHEMBL3815461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3811289	0.88	ROCK2 (0.64)	ROCK2ROCK1MAPK1HDAC1KDM1A
	SCHEMBL14009841	0.87	LMNA (0.53)	ROCK2ROCK1LMNAPOLBMAPK1
	SCHEMBL3810616	0.87	ROCK1 (0.55)	ROCK2ROCK1MAPK1
	SCHEMBL3816834	0.87	ROCK1 (0.56)	ROCK2ROCK1MAPK1
	SCHEMBL3816956	0.86	MAPK1 (0.62)	ROCK2ROCK1MAPK1HDAC1PRKACA
	SCHEMBL3821823	0.84	MLYCD (0.60)	ROCK2ROCK1MAPK1HDAC1KDM1A
	SCHEMBL3810618	0.84	ROCK2 (0.75)	ROCK2ROCK1HDAC1KDM1ACYP3A4
	SCHEMBL5099872	0.83	POLB (0.50)	ROCK2ROCK1LMNAPOLBALOX5
	SCHEMBL3818967	0.83	ROCK2 (0.47)	ROCK2ROCK1MAPK1HDAC1KDM1A
	SCHEMBL3818830	0.83	ROCK2 (0.59)	ROCK2ROCK1HDAC1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.