Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.88 |
| ▸ | RIN1 | Q13671 | 8/20 | 0.88 |
| ▸ | PPARG | P37231 | 5/20 | 0.88 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.88 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.88 |
| ▸ | IDE | P14735 | 2/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NSD2 | O96028 | 3/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049464 | 0.94 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL14956497 | 0.94 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL143997 | 0.94 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL13079427 | 0.94 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL143996 | 0.94 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL9037713 | 0.94 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL19739348 | 0.92 | ABL1 (0.97) | ABL1RIN1PPARGNR2E3NCOR2 | |
| Ammonia Solution, Strong SCHEMBL5943165 | 0.92 | ABL1 (0.97) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL9601528 | 0.92 | TDP1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| Iodoacetamide SCHEMBL20856939 | 0.87 | ABL1 (0.81) | ABL1RIN1PPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691984-B2 | Compounds and methods for DCAF-mediated protein degradation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230121082-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-04-20 | — | — | US | disclosed |
| EP-3864030-A1 | COMPOUNDS AND METHODS FOR DCAF-MEDIATED PROTEIN DEGRADATION | The Scripps Research Institute (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20210101884-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-04-08 | — | — | US | disclosed |
| US-20200190105-A1 | COMPOUNDS AND METHODS FOR DCAF-MEDIATED PROTEIN DEGRADATION | THE SCRIPPS RESEARCH INSTITUTE | 2020-06-18 | — | — | US | disclosed |
| WO-2019204740-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2019-10-24 | — | — | WO | disclosed |
| US-20120083599-A1 | Biomolecular Labelling Using Multifunctional Biotin Analogues | UNIVERSITY OF NOTTINGHAM (GB) | 2012-04-05 | — | — | US | disclosed |
| EP-2408783-A2 | BIOMOLECULAR LABELLING USING MULTIFUNCTIONAL BIOTIN ANALOGUES | University Of Nottingham (GB) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106347-A2 | BIOMOLECULAR LABELLING USING MULTIFUNCTIONAL BIOTIN ANALOGUES | UNIVERSITY OF NOTTINGHAM (GB) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083599-A1 | Biomolecular Labelling Using Multifunctional Biotin Analogues | BTD, URB2, RAET1L | ABL1 2957/4885RIN1 1985/4885PPARG 2465/4885 |
| US-20210101884-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | DGKA, DGKK, PRKG2 | ABL1 64/4885RIN1 297/4885PPARG 3145/4885 |
| US-20200190105-A1 | COMPOUNDS AND METHODS FOR DCAF-MEDIATED PROTEIN DEGRADATION | DCAF1, CUL4A, DCAF15 | ABL1 2648/4885RIN1 1116/4885PPARG 3523/4885 |
| US-11691984-B2 | Compounds and methods for DCAF-mediated protein degradation | DCAF1, CUL4A, DCAF15 | ABL1 2648/4885RIN1 1116/4885PPARG 3523/4885 |
| US-20230121082-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | DGKA, DGKK, PRKG2 | ABL1 64/4885RIN1 297/4885PPARG 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.