Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 1.00 |
| ▸ | RIN1 | Q13671 | 8/20 | 1.00 |
| ▸ | PPARG | P37231 | 5/20 | 1.00 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 1.00 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 1.00 |
| ▸ | IDE | P14735 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NSD2 | O96028 | 3/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13079427 | 1.00 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL14956497 | 1.00 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL143997 | 1.00 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL13049464 | 1.00 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL143996 | 1.00 | ABL1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| Ammonia Solution, Strong SCHEMBL5943165 | 0.98 | ABL1 (0.97) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL19739348 | 0.98 | ABL1 (0.97) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL9601528 | 0.98 | TDP1 (1.00) | ABL1RIN1PPARGNR2E3NCOR2 | |
| SCHEMBL381614 | 0.94 | ABL1 (0.88) | ABL1RIN1PPARGNR2E3NCOR2 | |
| Thiosulfuric Acid SCHEMBL6499597 | 0.91 | ABL1 (0.83) | ABL1RIN1PPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8256785-A | — | — | None | — | — | JP | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-10183965-B2 | Cofactor analogues for methyltransferases | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2019-01-22 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170283453-A1 | COFACTOR ANALOGUES FOR METHYLTRANSFERASES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-10-05 | — | — | US | disclosed |
| EP-3186266-A1 | S-ADENOSYL-L-CYSTEINE ANALOGUES AS COFACTORS FOR METHYLTRANSFERASES | Katholieke Universiteit Leuven (BE) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016030546-A1 | S-ADENOSYL-L-CYSTEINE ANALOGUES AS COFACTORS FOR METHYLTRANSFERASES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2016-03-03 | — | — | WO | disclosed |
| JP-H08256785-A | PRODUCTION OF D-DETHIOBIOTIN | F HOFFMANN LA ROCHE AG | 1996-10-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, MRPS18A | ABL1 4088/4885RIN1 1704/4885PPARG 3105/4885 |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | ABL1 4168/4885RIN1 1597/4885PPARG 3829/4885 |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | ABL1 4257/4885RIN1 2298/4885PPARG 3625/4885 |
| US-10183965-B2 | Cofactor analogues for methyltransferases | BHMT, BHMT2, NNMT | ABL1 2910/4885RIN1 3098/4885PPARG 3419/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | ABL1 3984/4885RIN1 813/4885PPARG 2792/4885 |
| US-20170283453-A1 | COFACTOR ANALOGUES FOR METHYLTRANSFERASES | BHMT, BHMT2, NNMT | ABL1 2876/4885RIN1 3128/4885PPARG 3414/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | ABL1 3984/4885RIN1 813/4885PPARG 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.