Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811541 | 0.85 | NPSR1 (0.48) | NPSR1KDM4ERXFP1ACLY | |
| SCHEMBL3816632 | 0.84 | NPSR1 (0.49) | NPSR1KDM4ERXFP1 | |
| SCHEMBL3816837 | 0.83 | NPSR1 (0.48) | NPSR1KDM4ERXFP1IKBKBACLY | |
| SCHEMBL2157587 | 0.83 | NPSR1 (0.54) | NPSR1KDM4ERXFP1IKBKBACLY | |
| SCHEMBL3808919 | 0.83 | NPSR1 (0.48) | NPSR1KDM4ERXFP1IKBKBACLY | |
| SCHEMBL3816971 | 0.83 | NPSR1 (0.48) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3809025 | 0.81 | ACLY (0.58) | NPSR1KDM4ERXFP1ACLY | |
| SCHEMBL3816575 | 0.81 | NPSR1 (0.67) | NPSR1KDM4ERXFP1IKBKBACLY | |
| SCHEMBL3812093 | 0.80 | NPSR1 (0.46) | NPSR1KDM4ERXFP1ACLY | |
| SCHEMBL3812325 | 0.80 | MEN1 (0.53) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |