Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815731 | 0.90 | HDAC6 (0.39) | MLYCDHDAC8NPSR1NPC1MAPT | |
| SCHEMBL3811259 | 0.88 | KDM4E (0.43) | MLYCDNPSR1MAPT | |
| SCHEMBL3816963 | 0.87 | USP2 (0.41) | MLYCDMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL3814669 | 0.86 | NTRK1 (0.43) | BACE1NPSR1HPGD | |
| SCHEMBL3809443 | 0.86 | HTR2C (0.41) | MLYCDNPSR1NPC1MAPTRAB9A | |
| SCHEMBL3812289 | 0.85 | MLYCD (0.44) | MLYCDHDAC8GPBAR1MEN1KMT2A | |
| SCHEMBL3807725 | 0.84 | HSD17B1 (0.43) | NPSR1NPC1MAPTRAB9A | |
| SCHEMBL3808967 | 0.83 | KAT6A (0.38) | MLYCDMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL3814624 | 0.82 | MLYCD (0.34) | MLYCDMEN1KMT2ANPSR1HPGD | |
| SCHEMBL3812631 | 0.82 | ACLY (0.41) | KMT2ANPSR1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |