Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157780 | 0.83 | MAPT (0.62) | MAPTTP53ATMALDH1A1HPGD | |
| SCHEMBL2158574 | 0.83 | PTPN1 (0.51) | MAPTTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL3815210 | 0.77 | ITGA1 (0.49) | NPSR1 | |
| SCHEMBL3817368 | 0.74 | HPGD (0.56) | MAPTTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL3816740 | 0.74 | HPGD (0.46) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3809006 | 0.74 | KMT2A (0.51) | MAPTTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL3814727 | 0.73 | NPSR1 (0.57) | ALDH1A1MEN1KMT2AIKBKBALOX12 | |
| SCHEMBL3809012 | 0.72 | NPSR1 (0.56) | KDM4ENPSR1 | |
| SCHEMBL3816592 | 0.72 | TRIM24 (0.46) | ALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL3812168 | 0.72 | ERCC1 (0.37) | MAPTTP53PTGDRHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |