Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209363 | 0.86 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7865566 | 0.85 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7992753 | 0.79 | POLB (0.42) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19797357 | 0.79 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2125699 | 0.79 | APP (0.47) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Alcohol SCHEMBL28130906 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28897681 | 0.78 | MAPT (0.35) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16585884 | 0.78 | MAPT (0.35) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7982222 | 0.77 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19797751 | 0.77 | APP (0.39) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102816112-B | Method for preparing pesticide nitenpyram | ZHEJIANG HEBEN PESTICIDE & CHEMICALS CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-102816112-A | Method for preparing pesticide nitenpyram | ZHEJIANG HEBEN PESTICIDE & CHEMICALS CO LTD | 2012-12-12 | — | — | CN | disclosed |
| EP-2094684-A2 | 1,5-DIPHENYL-3-BENZYLAMINO-1,5-DIHYDROPYRROLIDIN 2-ONES AS CB1 RECEPTOR MODULATORS | Eli Lilly & Company (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008070306-A2 | 1,5-DIPHENYL-3-BENZYLAMIN0-1,5-DIHYDR0PYRR0LIDIN-2-0NE AS CB1 RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |
| US-6160126-A | Synthetic Intermediates for the preparation of N, N'-Di-substituted isothiourea derivatives and N-cyclic(methyl)-N'-Substituted isothiourea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| US-5696256-A | CHEMICAL INTERMEDIATE FOR INSECTICIDES; MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0452782-B1 | Novel intermediates for preparing guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| EP-0452782-A1 | Novel intermediates for preparing guanidine derivatives, their preparation and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |