SCHEMBL7865566

SCHEMBL7865566

CCCN(C)c1ccc(Cl)nc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 2/20 0.39
HCAR3 P49019 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
DGAT1 O75907 1/20 0.38
TRPV1 Q8NER1 1/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5209363 0.90 MAPT (0.40) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL3817147 0.85 MAPT (0.46) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL7992753 0.84 POLB (0.42) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL19797357 0.84 MAPT (0.38) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL19797751 0.81 APP (0.39) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL7982222 0.81 ALDH1A1 (0.37) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL12781461 0.78 HCAR3 (0.38) MAPTHCAR3TRPV1
SCHEMBL7502123 0.77 MEN1 (0.36) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL2125699 0.76 APP (0.47) MAPTALDH1A1MEN1KMT2ALMNA
Alcohol SCHEMBL28130906 0.76 ALDH1A1 (0.43) MAPTALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001253872-A DERIVATIVE OF 6-CHLORO-3-PYRIDYLMETHYLPROPYLAMINE, METHOD FOR PREPARATION OF THE SAME AND MICROBICIDE KUREHA CHEM IND CO LTD 2001-09-18 JP disclosed