SCHEMBL7982222

SCHEMBL7982222

CN(CCCO)c1ccc(Cl)nc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 1/20 0.37
DGAT1 O75907 1/20 0.35
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992753 0.90 POLB (0.42) ALDH1A1MEN1KMT2ALMNADGAT1
SCHEMBL5209363 0.86 MAPT (0.40) ALDH1A1MEN1KMT2ALMNADGAT1
SCHEMBL19797751 0.83 APP (0.39) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL7865566 0.81 MAPT (0.40) ALDH1A1MEN1KMT2ALMNADGAT1
SCHEMBL2535002 0.80 EGFR (0.35) MAPTPOLBAPP
SCHEMBL7502123 0.80 MEN1 (0.36) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL19797357 0.79 MAPT (0.38) ALDH1A1MEN1KMT2ALMNAMAPT
SCHEMBL3817147 0.77 MAPT (0.46) ALDH1A1MEN1KMT2ALMNADGAT1
SCHEMBL28289217 0.77 CHRM1 (0.46) ALDH1A1KMT2ALMNAMAPTPOLB
Alcohol SCHEMBL28130906 0.75 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ALMNADGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297374-B1 Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them NIHON BAYER AGROCHEM K.K. (JP) 2001-10-02 US disclosed
US-6022967-A 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-08 US disclosed
US-5750704-A INSECTICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-05-12 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed