Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293902 | 0.74 | GSK3A (0.44) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL293409 | 0.72 | GSK3A (0.44) | POLBALDH1A1GAAHPGDMAPT | |
| SCHEMBL293972 | 0.72 | GSK3A (0.44) | POLBALDH1A1GAAHPGDMAPT | |
| SCHEMBL8917183 | 0.69 | ALDH1A1 (0.54) | POLBALDH1A1GAAHPGDLMNA | |
| SCHEMBL5444807 | 0.69 | DPP4 (0.41) | POLBALDH1A1GAAHPGDKMT2A | |
| SCHEMBL5450691 | 0.67 | MEN1 (0.43) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL8916983 | 0.67 | ALDH1A1 (0.46) | POLBALDH1A1GAAHPGDLMNA | |
| SCHEMBL4996201 | 0.66 | LMNA (0.50) | POLBALDH1A1GAALMNAMAPT | |
| SCHEMBL400760 | 0.65 | NR4A2 (0.48) | POLBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL28316970 | 0.65 | POLB (0.48) | POLBALDH1A1GAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828135-A4 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM LLC (BM) | 2009-08-12 | — | — | EP | claimed |
| EP-1828135-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM, LLC (BM) | 2007-09-05 | — | — | EP | claimed |
| WO-2006066011-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM LLC (BM) | 2006-06-22 | — | — | WO | claimed |