Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820055 | 0.78 | ALDH1A1 (0.48) | MMP1MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL3819295 | 0.78 | AR (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3817722 | 0.78 | MAPT (0.43) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3815007 | 0.77 | AR (0.44) | ALDH1A1KMT2AMAPK1PTK2B | |
| SCHEMBL3815729 | 0.77 | HPGD (0.51) | HPGDALDH1A1KMT2AMAPTHTT | |
| SCHEMBL3813194 | 0.76 | RAB9A (0.46) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3818288 | 0.76 | MAPT (0.48) | CA1CA2HPGDALDH1A1KMT2A | |
| SCHEMBL634086 | 0.76 | CA1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3815985 | 0.75 | LIPE (0.41) | MMP1MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL6230304 | 0.73 | MRGPRX4 (0.37) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513802-B1 | ALPHA-SULFONYLAMINO-ACETONITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-19 | — | — | EP | disclosed |
| US-7368479-B2 | Alpha-sulfonylamino-acetonitriles | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-7368479-B2 | Alpha-sulfonylamino-acetonitriles | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-7368479-B2 | Alpha-sulfonylamino-acetonitriles | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-20050234125-A1 | Alpha-sulfonylamino-acetonitriles | SYNGENTA CROP PROTECTION AG (CH) | 2005-10-20 | — | — | US | disclosed |
| EP-1513802-A1 | ALPHA-SULFONYLAMINO-ACETONITRILES | Syngenta Participations AG (CH) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000797-A1 | ALPHA-SULFONYLAMINO-ACETONITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234125-A1 | Alpha-sulfonylamino-acetonitriles | C3AR1, C1S, C5 | CA1 3613/4885CA2 3577/4885MMP1 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.