SCHEMBL3817469

SCHEMBL3817469

CC(C)c1ccc(-c2cc(-c3ccc(C(C)C)cc3)c(-n3ccnc3-c3ccc(F)cc3)c(-c3ccc(C(C)C)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.39
PLK2 Q9NYY3 3/20 0.39
PLK1 P53350 2/20 0.36
HCAR2 Q8TDS4 1/20 0.35
MAPK14 Q16539 3/20 0.34
MAPK13 O15264 2/20 0.34
MAPK12 P53778 2/20 0.34
MAPK11 Q15759 2/20 0.34
GCGR P47871 1/20 0.34
MAPT P10636 2/20 0.34
DGAT1 O75907 1/20 0.34
EGFR P00533 2/20 0.34
MAPK9 P45984 1/20 0.33
MAPK10 P53779 1/20 0.33
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3825222 0.86 TOP1 (0.39) PLK2PLK1MAPK9MAPK10PSEN1
SCHEMBL5576443 0.85 TOP1 (0.38) PLK2PLK1MAPK9MAPK10PSEN1
SCHEMBL3821581 0.84 TOP1 (0.45) MAPK14GCGRMAPTMAPK9MAPK10
SCHEMBL15315981 0.84 KDR (0.38) CYP17A1HCAR2MAPK14MAPTDGAT1
SCHEMBL4961113 0.78 PLK2 (0.40) CYP17A1PLK2PLK1HCAR2MAPK14
SCHEMBL26168531 0.78 MAPK9 (0.42) MAPK9MAPK10
SCHEMBL12797971 0.75 KDR (0.43) MAPK9MAPK10
SCHEMBL3833411 0.75 PLK2 (0.43) PLK2PLK1MAPK14MAPK13MAPK12
SCHEMBL16203605 0.74 KDR (0.39) MAPK9MAPK10
SCHEMBL12797952 0.74 FFAR1 (0.37) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127030-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-04-17 US disclosed
US-12171138-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-12-17 US disclosed
US-20220328774-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-13 US disclosed
CN-115160374-A Stable OLED materials and devices with improved stability 通用显示公司 2022-10-11 CN disclosed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
CN-107011388-A Stability OLED materials and the device with improved stability 通用显示公司 2017-08-04 CN disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
CN-101180304-B Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP. (US) 2015-08-19 CN disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220328774-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP2, EML4, OSBP CYP17A1 3841/4885PLK2 1869/4885PLK1 3482/4885
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 CYP17A1 3729/4885PLK2 2098/4885PLK1 2784/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 CYP17A1 3687/4885PLK2 2094/4885PLK1 2773/4885
US-20250127030-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP2, EML4, OSBP CYP17A1 3823/4885PLK2 1890/4885PLK1 3493/4885
US-12171138-B2 Organic electroluminescent materials and devices OSBP2, EML4, OSBP CYP17A1 3841/4885PLK2 1869/4885PLK1 3482/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 CYP17A1 3687/4885PLK2 2094/4885PLK1 2773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.