Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 10/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 4/20 | 0.36 |
| ▸ | FLT4 | P35916 | 4/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825222 | 0.99 | TOP1 (0.39) | TOP1PLK2ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL26168531 | 0.91 | MAPK9 (0.42) | KDRMAPK9MAPK10METAP2FLT1 | |
| SCHEMBL12797952 | 0.86 | FFAR1 (0.37) | TOP1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL3817469 | 0.85 | CYP17A1 (0.39) | PLK2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL3821581 | 0.85 | TOP1 (0.45) | TOP1KDRMAPK9MAPK10FLT1 | |
| SCHEMBL3816909 | 0.82 | TOP1 (0.42) | TOP1KDRFLT1FLT4 | |
| SCHEMBL12797947 | 0.81 | METAP2 (0.39) | KDRMAPK9MAPK10METAP2FLT1 | |
| SCHEMBL22370024 | 0.78 | MAPK9 (0.42) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL20375745 | 0.78 | CLK4 (0.40) | — | |
| SCHEMBL12797971 | 0.76 | KDR (0.43) | KDRMAPK9MAPK10FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902374-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| US-20070088167-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-20060251923-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2006-11-09 | — | — | US | disclosed |