Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810184 | 0.86 | MAPT (0.40) | MAPTHPGDRAB9ANPC1PTGS1 | |
| SCHEMBL3817576 | 0.81 | RAB9A (0.47) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL3811833 | 0.80 | MAPT (0.52) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL3810180 | 0.80 | MAPT (0.47) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL27573189 | 0.80 | KMT2A (0.35) | MAPTHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL3813294 | 0.79 | NPC1 (0.46) | MAPTHPGDRAB9ANPC1PTGS1 | |
| SCHEMBL3809482 | 0.77 | KMT2A (0.45) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3812073 | 0.75 | MEN1 (0.35) | MAPTRAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27573190 | 0.74 | ALDH1A1 (0.43) | MAPTHPGDRAB9ANPC1PTGS1 | |
| SCHEMBL3808063 | 0.70 | ALDH1A1 (0.34) | MAPTRAB9AALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341786-B9 | SUBSTITUTED DERIVATIVES OF AMINOFURAN-2-YL-ACETIC ACID AND AMINOTHIEN-2-YL-ACETIC ACID AND THE USE THEREOF FOR TREATING MIGRAINES AND PAIN | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| EP-1341786-B1 | SUBSTITUTED DERIVATIVES OF AMINOFURAN-2-YL-ACETIC ACID AND AMINOTHIEN-2-YL-ACETIC ACID AND THE USE THEREOF FOR TREATING MIGRAINES AND PAIN | GRUENENTHAL GMBH (DE) | 2008-12-24 | — | — | EP | claimed |