Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124694 | 0.83 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL3397689 | 0.83 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL20576145 | 0.83 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8472422 | 0.83 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL18359864 | 0.83 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8472423 | 0.83 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL27880889 | 0.82 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL3092249 | 0.82 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL7276228 | 0.82 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL11018000 | 0.82 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1625153-A1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099239-A1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |