Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27880889 | 1.00 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL11599332 | 0.90 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL11597784 | 0.89 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL9807251 | 0.87 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL11018000 | 0.87 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8472423 | 0.85 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL18359864 | 0.85 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL9124694 | 0.85 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL20576145 | 0.85 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8472422 | 0.85 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012712-A1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | FOREST LABORATORIES HOLDINGS LTD. (BM) | 2013-01-10 | — | — | US | disclosed |
| US-8288553-B2 | Method for preparing disubstituted piperidine and intermediates | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2012-10-16 | — | — | US | disclosed |
| EP-2200983-B1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | NOVEXEL (FR) | 2011-12-28 | — | — | EP | disclosed |
| US-20100197928-A1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | NOVEXEL (FR) | 2010-08-05 | — | — | US | disclosed |
| EP-2200983-A1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | NOVEXEL (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009090320-A1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | NOVEXEL (FR) | 2009-07-23 | — | — | WO | disclosed |
| EP-0353565-B1 | IMMUNOSTIMULATING PEPTIDES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMMPOSITIONS CONTAINING THEM | ELLEM INDUSTRIA FARMACEUTICA S.p.A. (IT) | 1993-03-24 | — | — | EP | disclosed |
| US-5079231-A | IMMUNOSTIMULATING PEPTIDES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELLEM INDUSTRIA FARMACEUTICA S.P.A. (IT) | 1992-01-07 | — | — | US | disclosed |
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0353565-A1 | Immunostimulating peptides, a process for their preparation and pharmaceutical commpositions containing them | ELLEM INDUSTRIA FARMACEUTICA S.p.A. (IT) | 1990-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012712-A1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | OGDH, FPGS, PLOD1 | L3MBTL1 4505/4885ALDH1A1 449/4885LMNA 1919/4885 |
| US-20100197928-A1 | METHOD FOR PREPARING DISUBSTITUTED PIPERIDINE AND INTERMEDIATES | OGDH, FPGS, PLOD1 | L3MBTL1 4505/4885ALDH1A1 449/4885LMNA 1919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.