SCHEMBL381803

SCHEMBL381803

Cc1cc(Cl)ncc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MAPT P10636 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
TSHR P16473 5/20 0.40
HSD17B10 Q99714 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 2/20 0.39
RECQL P46063 1/20 0.39
GPR35 Q9HC97 2/20 0.38
GAA P10253 1/20 0.38
PIN1 Q13526 1/20 0.38
MAPK1 P28482 1/20 0.37
AHR P35869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390182 1.00 ALDH1A1 (0.49) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL2669593 0.85 TSHR (0.43) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL30749766 0.85 TSHR (0.43) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL29987444 0.83 TSHR (0.42) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL30197179 0.80 ALDH1A1 (0.51) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL57316 0.80 TSHR (0.48) ALDH1A1MAPTTSHRSMN1; SMN2CYP3A4
SCHEMBL29467181 0.80 TSHR (0.48) ALDH1A1MAPTTSHRSMN1; SMN2CYP3A4
SCHEMBL843761 0.80 ALDH1A1 (0.51) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL3085354 0.78 ALDH1A1 (0.50) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL15881241 0.78 SMN1; SMN2 (0.41) ALDH1A1MAPTTSHRSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557886-B Synthesis method of 3-nitroisonicotinic acid methyl ester 山西永津集团有限公司 2024-09-27 CN claimed
CN-116574455-A High-temperature-resistant flexible polyimide anti-counterfeiting label material and preparation method thereof 安徽融优新材料科技有限公司 2023-08-11 CN claimed
CN-115557886-A Synthetic method of 3-nitroisonicotinic acid methyl ester 山西永津集团有限公司 2023-01-03 CN claimed
CN-105541703-A Triamine monomer containing pyridine structure and preparation method thereof UNIV JILIN 2016-05-04 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2026-05-14 US disclosed
EP-4725493-A2 POLYCYCLIC COMPOUNDS FOR INHIBITING RNA HELICASE DHX33 AND USE THEREOF Shenzhen Keye Life Technologies, Co., Ltd. (CN) 2026-04-15 EP disclosed
US-12589156-B2 Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (LRRK2) ARVINAS OPERATIONS, INC. (US) 2026-03-31 US disclosed
US-20260078127-A1 HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 BOEHRINGER INGELHEIM INT (DE) 2026-03-19 US disclosed
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2026-03-19 US disclosed
US-12559506-B2 Indazole based compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
EP-0379314-B1 3-(1,2,5,6-Tetrahydropyridyl)-pyrrolopyridines PFIZER (US) 1994-03-23 EP disclosed
US-5169947-A 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines PFIZER INC. (US) 1992-12-08 US disclosed
US-5051412-A Pharmaceutically active 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines PFIZER INC. (US) 1991-09-24 US disclosed
EP-0429987-A2 5,11-Dihydro-6H-dipyrido[3,2-b:2',3'-e] [1,4]diazepines and their use in the prevention or treatment of HIV infection BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1991-06-05 EP disclosed
CN-1044465-A 3-(1,2,5, the 6-tetrahydro pyridyl)-pyrrolopyridine PFIZER (US) 1990-08-08 CN disclosed
WO-1990007926-A1 3-(1,2,5,6-TETRAHYDROPYRIDYL)-PYRROLOPYRIDINES PFIZER INC. (US) 1990-07-26 WO disclosed
EP-0379314-A1 3-(1,2,5,6-Tetrahydropyridyl)-pyrrolopyridines PFIZER INC. (US) 1990-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, IRF3, CGAS ALDH1A1 3829/4885MAPT 3909/4885CYP1A2 4348/4885
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer TP53, HIF1AN, MDM2 ALDH1A1 821/4885MAPT 3905/4885CYP1A2 2795/4885
US-12559506-B2 Indazole based compounds and associated methods of use LRRK2, CRBN, CLK2 ALDH1A1 3579/4885MAPT 187/4885CYP1A2 2912/4885
US-20260078127-A1 HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 CD38, CD22, CD79B ALDH1A1 877/4885MAPT 4832/4885CYP1A2 1705/4885
US-12589156-B2 Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (LRRK2) LRRK2, SNCA, PARK7 ALDH1A1 3225/4885MAPT 250/4885CYP1A2 4771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.