Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467181 | 1.00 | TSHR (0.48) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL12489778 | 0.83 | TSHR (0.44) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL32681751 | 0.82 | TSHR (0.42) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL17512681 | 0.80 | TDP1 (0.46) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL15270693 | 0.80 | ALDH1A1 (0.44) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL381803 | 0.80 | ALDH1A1 (0.49) | TSHRMAPK1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL563628 | 0.80 | TDP1 (0.46) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL17506477 | 0.80 | AAK1 (0.40) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL29390182 | 0.80 | ALDH1A1 (0.49) | TSHRMAPK1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL619628 | 0.80 | TSHR (0.46) | TSHRMAPK1ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493436-B | Amino substituted pyridine derivative and preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2023-10-20 | — | — | CN | claimed |
| CN-113493436-A | Amino-substituted pyridine derivative and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-10-12 | — | — | CN | claimed |
| US-20260098028-A1 | Compounds and Their Use for Treatment of Hemoglobinopathies | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260062427-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20260049093-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-02-19 | — | — | US | disclosed |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4680607-A1 | BICYCLIC UREAS AS KINASE INHIBITORS | Incyte Corporation (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4225739-B1 | PREPARATION OF BENZIMIDAZOLONE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12528791-B2 | Thyroid hormone receptor beta agonist compounds | TERNS PHARMACEUTICALS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| EP-1490367-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-29 | — | — | EP | disclosed |
| WO-2004076454-A1 | DIHYDROPTERIDINONES, METHOD FOR THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) | 2004-09-10 | — | — | WO | disclosed |
| US-20040176380-A1 | New dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH CO. KG (DE) | 2004-09-09 | — | — | US | disclosed |
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2003080610-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |
| EP-0400583-B1 | Imidazoquinoxalinones, their aza analogs and process for their preparation | BERLEX LAB (US) | 1999-11-17 | — | — | EP | disclosed |
| US-5166344-A | Process for the preparation of imidazoquinoxalinones | BERLEX LABORATORIES, INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5055465-A | IMIDAZOQUINOXALINONES, THEIR AZA ANALOGS AND PROCESS FOR THEIR PREPARATION | BERLEX LABORATORIES, INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0400583-A1 | Imidazoquinoxalinones, their aza analogs and process for their preparation | BERLEX LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049093-A1 | Bicyclic Ureas As Kinase Inhibitors | OXSR1, JAK1, NCOR1 | TSHR 157/4885MAPK1 28/4885ALDH1A1 1726/4885 |
| US-20040176380-A1 | New dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions | QDPR, DHPS, DRD5 | TSHR 3992/4885MAPK1 3107/4885ALDH1A1 608/4885 |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | TSHR 1671/4885MAPK1 899/4885ALDH1A1 1935/4885 |
| US-12528791-B2 | Thyroid hormone receptor beta agonist compounds | THRB, THRA, TSHR | TSHR 3/4885MAPK1 2095/4885ALDH1A1 2577/4885 |
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | NR0B1, NR2C2, ERBB2 | TSHR 226/4885MAPK1 68/4885ALDH1A1 2073/4885 |
| US-20260062427-A1 | Bicyclic Ureas As Kinase Inhibitors | OXSR1, NCOR1, NR0B1 | TSHR 106/4885MAPK1 32/4885ALDH1A1 2038/4885 |
| US-20260098028-A1 | Compounds and Their Use for Treatment of Hemoglobinopathies | HBZ, HBG2, HBB | TSHR 2323/4885MAPK1 4218/4885ALDH1A1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.