Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | DRD3 | P35462 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 8/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382100 | 0.90 | ITGB3 (0.46) | USP30ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL383372 | 0.89 | ITGB3 (0.42) | USP30ITGB3ITGAVITGA2B | |
| SCHEMBL383051 | 0.87 | ITGB3 (0.54) | USP30ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL381765 | 0.86 | ALDH1A1 (0.46) | DRD2DRD3 | |
| SCHEMBL382568 | 0.85 | ITGB3 (0.43) | USP30ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL383235 | 0.85 | ITGB3 (0.48) | USP30ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL382513 | 0.85 | ITGB3 (0.49) | USP30ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL382188 | 0.85 | ITGB3 (0.49) | USP30ITGB3ITGAVITGA2BDRD2 | |
| SCHEMBL6496334 | 0.84 | CNR1 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL382297 | 0.84 | ITGB3 (0.44) | ITGB3ITGAVITGA2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |