Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | DRD3 | P35462 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 5/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496334 | 0.91 | CNR1 (0.43) | DRD2DRD3KDM4EHTTCNR1 | |
| SCHEMBL6800155 | 0.90 | ALDH1A1 (0.44) | ALDH1A1GFERDRD2DRD3KDM4E | |
| SCHEMBL7539445 | 0.89 | CNR1 (0.44) | ALDH1A1GFERDRD2DRD3KDM4E | |
| SCHEMBL382963 | 0.88 | SMYD3 (0.43) | ALDH1A1GFERDRD2DRD3KDM4E | |
| SCHEMBL6801441 | 0.87 | ALDH1A1 (0.41) | ALDH1A1GFERDRD2DRD3KDM4E | |
| SCHEMBL383372 | 0.87 | ITGB3 (0.42) | JAK2JAK3 | |
| SCHEMBL381827 | 0.86 | USP30 (0.45) | DRD2DRD3 | |
| SCHEMBL382763 | 0.85 | ITGB3 (0.48) | GFERDRD2DRD3KDM4EHTT | |
| SCHEMBL7540512 | 0.84 | DRD2 (0.41) | ALDH1A1GFERDRD2DRD3CASR | |
| SCHEMBL382409 | 0.83 | KDM4E (0.40) | DRD2DRD3KDM4EHTTCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |