SCHEMBL3818976

SCHEMBL3818976

CC(C)c1[c]c(C(C)C)cc(C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.38
ALB P02768 2/20 0.38
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GLA P06280 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2A6 P11509 1/20 0.32
VCAM1 P19320 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817420 0.81 EGLN2 (0.33) ALDH1A1CYP2A6
SCHEMBL8896553 0.74 GLA (0.37) GLAALDH1A1CYP2A6HDAC8
SCHEMBL2177186 0.73 HTT (0.32)
SCHEMBL10880463 0.72 TTR (0.42) TTRALBMEN1KMT2AGLA
SCHEMBL6667915 0.70 TTR (0.41) TTRALBMEN1KMT2AGLA
SCHEMBL145914 0.69 GABRA1 (0.36) ALDH1A1
SCHEMBL1395973 0.69 NOS3 (0.34) ALDH1A1
SCHEMBL2154261 0.68 TTR (0.39) TTRALBMEN1KMT2AGLA
SCHEMBL21625522 0.67
SCHEMBL7618662 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US claimed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US claimed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP claimed
CN-115160374-A Stable OLED materials and devices with improved stability 通用显示公司 2022-10-11 CN disclosed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
CN-107011388-A Stability OLED materials and the device with improved stability 通用显示公司 2017-08-04 CN disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
CN-101180304-B Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP. (US) 2015-08-19 CN disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
CN-102775447-A Stability OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP 2012-11-14 CN disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
CN-101180304-A Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP (US) 2008-05-14 CN disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 TTR 1101/4885ALB 1381/4885MEN1 3298/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 TTR 1062/4885ALB 1380/4885MEN1 3324/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 TTR 1062/4885ALB 1380/4885MEN1 3324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.