Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18193010 | 0.90 | IDO1 (0.35) | LMNAHTTIDO1TDO2 | |
| SCHEMBL3818629 | 0.77 | MEN1 (0.37) | MEN1KMT2ASMN1; SMN2TERT | |
| SCHEMBL9401207 | 0.68 | NPC1 (0.34) | LMNAMAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL2559434 | 0.68 | IDO1 (0.38) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL3817562 | 0.67 | NPSR1 (0.42) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL21495057 | 0.66 | IDO1 (0.37) | HTTIDO1TDO2 | |
| SCHEMBL166469 | 0.66 | IDO1 (0.37) | HTTIDO1TDO2 | |
| SCHEMBL15142385 | 0.66 | MME (0.43) | MEN1KMT2AHTTNPSR1 | |
| SCHEMBL22445604 | 0.65 | IDO1 (0.40) | HTTIDO1TDO2 | |
| SCHEMBL9818286 | 0.65 | HTT (0.42) | LMNAHTTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091527-A2 | SULFIDE, SULFOXIDE AND SULFONE CHALCONE ANALOGUES, DERIVATIVES THEREOF AND THERAPEUTIC USES THEREOF | Temple University of the Commonwealth System of Higher Education (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008076270-A2 | SULFIDE, SULFOXIDE AND SULFONE CHALCONE ANALOGUES, DERIVATIVES THEREOF AND THERAPEUTIC USES THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-06-26 | — | — | WO | disclosed |