Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818629 | 0.87 | MEN1 (0.37) | MEN1KMT2AMAOAMAOBCYP2A6 | |
| SCHEMBL20425444 | 0.83 | MTNR1A (0.42) | LMNAKMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8057378 | 0.77 | MAPT (0.50) | NPSR1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9401376 | 0.72 | L3MBTL1 (0.34) | NPSR1LMNAMAPTRAB9AALDH1A1 | |
| SCHEMBL27907017 | 0.70 | ALDH1A1 (0.50) | NPSR1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9301 | 0.70 | — | — | |
| SCHEMBL14048314 | 0.69 | MEN1 (0.52) | NPSR1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7148548 | 0.69 | NFE2L2 (0.44) | KMT2ARAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL9621498 | 0.68 | ALDH1A1 (0.42) | LMNAMEN1KMT2AMAPTRAB9A | |
| Magnesium SCHEMBL31191739 | 0.68 | CA1 (0.65) | NPSR1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091527-A2 | SULFIDE, SULFOXIDE AND SULFONE CHALCONE ANALOGUES, DERIVATIVES THEREOF AND THERAPEUTIC USES THEREOF | Temple University of the Commonwealth System of Higher Education (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008076270-A2 | SULFIDE, SULFOXIDE AND SULFONE CHALCONE ANALOGUES, DERIVATIVES THEREOF AND THERAPEUTIC USES THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-06-26 | — | — | WO | disclosed |