SCHEMBL9401207

SCHEMBL9401207

COc1cc(OC)nc(SC(C=O)c2ccccc2Br)n1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
XBP1 P17861 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
PAX8 Q06710 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PTGES O14684 2/20 0.33
ALOX5 P09917 2/20 0.33
CTSA P10619 1/20 0.33
PPARG P37231 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401252 0.85 CTSA (0.43) ALDH1A1CTSA
SCHEMBL9401279 0.84 NPSR1 (0.37) SMN1; SMN2NPSR1CTSA
SCHEMBL9401531 0.84 EDNRB (0.37) NPC1ALDH1A1LMNARAB9ACTSA
SCHEMBL9401440 0.81 PTGES (0.40) MAPTPTGESALOX5PPARG
SCHEMBL9401386 0.81 NPC1 (0.36) NPC1ALDH1A1MAPTRAB9A
SCHEMBL9401376 0.78 L3MBTL1 (0.34) NPC1ALDH1A1LMNAGAAMAPT
SCHEMBL9401303 0.77 CTSA (0.34) ALDH1A1CTSA
SCHEMBL9401347 0.76 MEN1 (0.39)
SCHEMBL9401325 0.75 HTT (0.36) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL9572237 0.74 EDNRB (0.36) ALDH1A1LMNASMN1; SMN2PTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346880-A Pre- and postemergence NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0565951-A1 Herbicidally active pyrimidinylthioalkane derivatives NIHON BAYER AGROCHEM K.K. (JP) 1993-10-20 EP disclosed