SCHEMBL3820141

SCHEMBL3820141

Cc1c(C)c(C)c(-n2ccnc2-c2ccccc2)c(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDR P35968 16/20 0.48
FLT1 P17948 3/20 0.46
FLT4 P35916 3/20 0.46
MAPK9 P45984 1/20 0.44
MAPK10 P53779 1/20 0.44
ESR1 P03372 1/20 0.42
HPGDS O60760 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17472955 0.86 KDR (0.46) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL3817755 0.85 KDR (0.51) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL28015972 0.84 KDR (0.50) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL28566945 0.82 KDR (0.49) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL1316463 0.82 KDR (0.52) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL3815157 0.82 KDR (0.46) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL3833411 0.81 PLK2 (0.43) MAPK9MAPK10
SCHEMBL25564159 0.81 KDR (0.46) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL29070232 0.81 KDR (0.51) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL15316080 0.81 KDR (0.43) KDRFLT1FLT4MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160374-A Stable OLED materials and devices with improved stability 通用显示公司 2022-10-11 CN disclosed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
CN-107011388-A Stability OLED materials and the device with improved stability 通用显示公司 2017-08-04 CN disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
CN-101180304-B Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP. (US) 2015-08-19 CN disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 KDR 1067/4885FLT1 4196/4885FLT4 3603/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 KDR 1148/4885FLT1 4252/4885FLT4 3664/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 KDR 1148/4885FLT1 4252/4885FLT4 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.