SCHEMBL28566945

SCHEMBL28566945

c1ccc(-c2nccn2-c2ncccn2)cc1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDR P35968 17/20 0.49
MAPK9 P45984 1/20 0.45
MAPK10 P53779 1/20 0.45
ESR1 P03372 1/20 0.44
FLT1 P17948 3/20 0.43
FLT4 P35916 3/20 0.43
RPS6KA5 O75582 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29526693 0.92 MAPK9 (0.44) KDRMAPK9MAPK10ESR1FLT1
SCHEMBL9026902 0.88 KDR (0.53) KDRMAPK9MAPK10ESR1FLT1
SCHEMBL15746078 0.83 KDR (0.49) KDRMAPK9MAPK10FLT1FLT4
SCHEMBL3820141 0.82 KDR (0.48) KDRMAPK9MAPK10ESR1FLT1
SCHEMBL28588429 0.82 MAPK9 (0.38) KDRMAPK9MAPK10FLT1FLT4
Benzene SCHEMBL27839441 0.82 MAPK9 (0.54) KDRMAPK9MAPK10ESR1FLT1
SCHEMBL528245 0.82 MAPK9 (0.54) KDRMAPK9MAPK10ESR1FLT1
SCHEMBL5594263 0.81 KDR (0.57) KDRFLT1FLT4
Hydrochloric Acid SCHEMBL27683877 0.80 MAPK9 (0.53) KDRMAPK9MAPK10ESR1FLT1
SCHEMBL5698561 0.77 MAPK9 (0.62) KDRMAPK9MAPK10ESR1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112877698-A Pyrimidine imidazoline corrosion inhibitor and preparation method thereof 李艳艳 2021-06-01 CN claimed
CN-112876459-B Multi-cation benzimidazole corrosion inhibitor and preparation method thereof 天津市科达斯实业有限公司 2022-04-01 CN disclosed
CN-112877698-A Pyrimidine imidazoline corrosion inhibitor and preparation method thereof 李艳艳 2021-06-01 CN disclosed
CN-112877698-A Pyrimidine imidazoline corrosion inhibitor and preparation method thereof 李艳艳 2021-06-01 CN disclosed
CN-112876459-A Multi-cation benzimidazole corrosion inhibitor and preparation method thereof 李艳艳 2021-06-01 CN disclosed