Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363230 | 1.00 | AR (0.69) | ARCYP2C19 | |
| SCHEMBL19243489 | 0.90 | AR (0.69) | ARCYP2C19 | |
| SCHEMBL14878986 | 0.90 | AR (0.69) | ARCYP2C19 | |
| SCHEMBL20113379 | 0.90 | AR (0.69) | ARCYP2C19 | |
| SCHEMBL22626571 | 0.89 | AR (0.66) | ARCYP2C19 | |
| SCHEMBL22560838 | 0.89 | AR (0.68) | ARCYP2C19 | |
| SCHEMBL110581 | 0.89 | AR (0.68) | ARCYP2C19 | |
| SCHEMBL20646260 | 0.89 | AR (0.68) | ARCYP2C19 | |
| SCHEMBL5360052 | 0.89 | AR (0.68) | ARCYP2C19 | |
| SCHEMBL14517806 | 0.89 | AR (0.68) | ARCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199257-B1 | Process for the synthesis of N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-03 | — | — | US | claimed |
| EP-1189898-B1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZET (HU) | 2003-03-12 | — | — | EP | claimed |
| EP-1189898-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-03-27 | — | — | EP | claimed |
| WO-2001000608-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2001-01-04 | — | — | WO | claimed |
| EP-1462442-B1 | CRYSTALS OF BICALUTAMIDE AND PROCESS FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2009-08-26 | — | — | EP | disclosed |
| US-7323584-B2 | Process for preparing N-(4′-cyano-3′-trifluoromethylphenyl)-3-(4″-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | HELM AG (DE) | 2008-01-29 | — | — | US | disclosed |
| US-7323584-B2 | Process for preparing N-(4′-cyano-3′-trifluoromethylphenyl)-3-(4″-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | HELM AG (DE) | 2008-01-29 | — | — | US | disclosed |
| US-7199257-B1 | Process for the synthesis of N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-03 | — | — | US | disclosed |
| US-7199257-B1 | Process for the synthesis of N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-03 | — | — | US | disclosed |
| US-7199257-B1 | Process for the synthesis of N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-03 | — | — | US | disclosed |
| US-7186854-B2 | Process for making bicalutamide and intermediates thereof | SYNTHON IP INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186854-B2 | Process for making bicalutamide and intermediates thereof | SYNTHON IP INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-20030073742-A1 | Process for making bicalutamide and intermediates thereof | SYNTHON B.V. (NL) | 2003-04-17 | — | — | US | disclosed |
| EP-1189898-B1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZET (HU) | 2003-03-12 | — | — | EP | disclosed |
| EP-1189898-B1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZET (HU) | 2003-03-12 | — | — | EP | disclosed |
| EP-1189898-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-03-27 | — | — | EP | disclosed |
| EP-1189898-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000608-A8 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZET (HU) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001000608-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000608-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073742-A1 | Process for making bicalutamide and intermediates thereof | BLVRB, BRDT, OTUB1 | AR 15/4885CYP2C19 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.