Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817988 | 0.96 | EPHX1 (0.54) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| Hydrochloric Acid SCHEMBL4910410 | 0.82 | EPHX1 (0.56) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL22322971 | 0.81 | HTR2A (0.59) | EPHX1ALOX5LMNAHTR2ATSHR | |
| SCHEMBL4903456 | 0.81 | CHRM1 (0.41) | EPHX1ALOX5LMNAHTR2ACHRM1 | |
| Hydrochloric Acid SCHEMBL4911395 | 0.76 | EPHX1 (0.49) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL4912298 | 0.74 | EPHX1 (0.47) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL4743213 | 0.74 | EPHX1 (0.50) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| Hydrochloric Acid SCHEMBL4423787 | 0.74 | EPHX1 (0.50) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL14798227 | 0.73 | EPHX1 (0.49) | EPHX1ALOX5PTGS1PTGS2CXCR1 | |
| SCHEMBL13254979 | 0.73 | TSHR (0.52) | EPHX1ALOX5PTGS1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | EPHX1 79/4885ALOX5 166/4885PTGS1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.