Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740364 | 0.87 | SIRT6 (0.41) | SERPINE1SIRT6TMEM97MAPTMAPK1 | |
| SCHEMBL9983972 | 0.84 | SERPINE1 (0.46) | SERPINE1SIRT6TMEM97MAPTMAPK1 | |
| SCHEMBL2126718 | 0.83 | CCNC (0.40) | SIRT6TMEM97MAPTMAPK1HTT | |
| SCHEMBL2126360 | 0.82 | SERPINE1 (0.45) | SERPINE1MAPTHTTALDH1A1LMNA | |
| SCHEMBL15740464 | 0.82 | SIRT6 (0.41) | SERPINE1SIRT6TMEM97MAPTMAPK1 | |
| SCHEMBL15740478 | 0.82 | SIRT6 (0.41) | SERPINE1SIRT6TMEM97MAPTMAPK1 | |
| SCHEMBL15740352 | 0.82 | SIRT6 (0.41) | SIRT6TMEM97MAPTMAPK1NPSR1 | |
| SCHEMBL2124654 | 0.82 | MALT1 (0.37) | TMEM97MAPK1HTTALDH1A1LMNA | |
| SCHEMBL2126004 | 0.81 | SIRT6 (0.40) | SIRT6TMEM97MAPTMAPK1HTT | |
| SCHEMBL15740426 | 0.80 | HRH3 (0.42) | SERPINE1SIRT6TMEM97MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408742-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010115688-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-10-14 | — | — | WO | disclosed |