Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.36 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | AADAC | P22760 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126718 | 0.85 | CCNC (0.40) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL15740370 | 0.82 | POLB (0.37) | TMEM97SMN1; SMN2 | |
| SCHEMBL382069 | 0.82 | SERPINE1 (0.42) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL2126360 | 0.82 | SERPINE1 (0.45) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2125848 | 0.81 | SERPINE1 (0.37) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL2124155 | 0.81 | SERPINE1 (0.37) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL2126004 | 0.80 | SIRT6 (0.40) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL2125198 | 0.80 | MEN1 (0.40) | ALDH1A1LMNACYP2C9MAPK1CYP2C19 | |
| SCHEMBL2617769 | 0.79 | ENPP2 (0.41) | MALT1TMEM97ARCYP3A4CES2 | |
| SCHEMBL2123344 | 0.79 | ENPP2 (0.41) | MALT1TMEM97ARCYP3A4CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |