Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367189 | 0.81 | CTSK (0.48) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL903742 | 0.81 | CTSK (0.48) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL2367381 | 0.81 | CTSK (0.48) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL5203895 | 0.80 | CYP3A4 (0.46) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL14190234 | 0.76 | CTSS (0.47) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL27245127 | 0.74 | CTSK (0.56) | CTSKCTSSJAK3BTK | |
| SCHEMBL27245117 | 0.74 | CTSK (0.56) | CTSKCTSSJAK3BTK | |
| SCHEMBL3820797 | 0.74 | MMP13 (0.36) | CTSKCTSSCTSLCTSB | |
| SCHEMBL3826119 | 0.73 | CTSK (0.49) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL8706268 | 0.73 | ACE (0.58) | CTSKCTSSCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |