Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216094 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL27676707 | 0.86 | PTPN11 (0.56) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL6948220 | 0.86 | LMNA (0.46) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL382128 | 0.86 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28602270 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL7695345 | 0.84 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL13951454 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL29263206 | 0.84 | PTPN1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL383490 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL29057024 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |