SCHEMBL382168

SCHEMBL382168

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(O)C(O)CO

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.54
ALDH1A1 P00352 2/20 0.54
CNR2 P34972 2/20 0.54
FAAH O00519 3/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
TRPV1 Q8NER1 1/20 0.49
TRPM8 Q7Z2W7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3992125 1.00 CNR1 (0.54) CNR1ALDH1A1CNR2FAAHMAPT
SCHEMBL2710460 0.98 ALDH1A1 (0.53) CNR1ALDH1A1CNR2HPGDTRPV1
SCHEMBL4619981 0.98 ALDH1A1 (0.53) CNR1ALDH1A1CNR2HPGDTRPV1
SCHEMBL1962550 0.93 SPHK1 (0.53) ALDH1A1MAPT
SCHEMBL1101078 0.93 SPHK1 (0.53) ALDH1A1MAPT
SCHEMBL27454783 0.93 SPHK1 (0.53) ALDH1A1MAPT
SCHEMBL8574566 0.93 SPHK1 (0.53) ALDH1A1MAPT
SCHEMBL1963079 0.93 SPHK1 (0.53) ALDH1A1MAPT
SCHEMBL314278 0.93 SPHK1 (0.53) ALDH1A1MAPT
SCHEMBL2232599 0.93 SPHK1 (0.53) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110077239-A1 GLYCINE RECEPTOR AGONISTS FOR THE TREATMENT OF PHANTOM PHENOMENA EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKLINIKUM (DE) 2011-03-31 US claimed
WO-2009073788-A1 COMPOSITIONS AND METHODS FOR TREATING MENOPAUSAL FEMALES FIRESTONE LEIGH H (US) 2009-06-11 WO claimed
WO-2001085158-A2 ANANDAMIDE AND STRUCTURALLY RELATED LIPIDS AS VANILLOID RECEPTOR MODULATORS FORSKARPATENT I SYD AB (SE) 2001-11-15 WO claimed
EP-4618987-A1 METHODS FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE BY MODULATING OR INHIBITING CANNABINOID RECEPTOR 1 Joyboy The Igwe L.L.C. (US) 2025-09-24 EP disclosed
WO-2024129891-A1 METHODS FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE BY MODULATING OR INHIBITING CANNABINOID RECEPTOR 1 JOYBOY THE IGWE L.L.C. (US) 2024-06-20 WO disclosed
US-20190156919-A1 DETERMINING RELATIONSHIPS BETWEEN RISKS FOR BIOLOGICAL CONDITIONS AND DYNAMIC ANALYTES ARIVALE, INC. (US) 2019-05-23 US disclosed
CN-109715613-A Heterocyclic compound 武田药品工业株式会社 2019-05-03 CN disclosed
EP-2569445-A1 SCREENING ASSAYS BASED ON MAG AND/OR ABHD6 FOR SELECTING INSULIN SECRETION PROMOTING AGENTS Val-Chlum, Limited Partnership (CA) 2013-03-20 EP disclosed
US-8323680-B1 Nutritional composition NESTEC S.A. (CH) 2012-12-04 US disclosed
US-20120252865-A1 CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2012-10-04 US disclosed
EP-2408743-A1 CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) 2012-01-25 EP disclosed
EP-1084098-A4 INHIBITORS OF THE ANANDAMIDE TRANSPORTER AS ANALGESIC AGENTS UNIV CONNECTICUT (US) 2004-12-22 EP disclosed
WO-2004105699-A2 COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CANNABINOID AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE PHARMACIA CORPORATION (US) 2004-12-09 WO disclosed
WO-2004012727-A1 COMPOSITIONS COMPRISING POLYSATURATED FATTY ACID (PUFAS) FOR THE CONTROL OF APPETITE AND BODY WEIGHT MANAGEMENT ABBOTT LABORATORIES (US) 2004-02-12 WO disclosed
EP-1307585-A1 COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING COX-2 ACTIVITY AND 2-ARACHIDONYLGLYCEROL METABOLITES VANDERBILT UNIVERSITY (US) 2003-05-07 EP disclosed
US-20020064804-A1 Compositions and methods for detecting and quantifying COX-2 activity and 2-arachidonylglycerol metabolites VANDERBILT UNIVERSITY 2002-05-30 US disclosed
WO-2002012549-A1 COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING COX-2 ACTIVITY AND 2-ARACHIDONYLGLYCEROL METABOLITES VANDERBILT UNIVERSITY (US) 2002-02-14 WO disclosed
WO-2001085158-A2 ANANDAMIDE AND STRUCTURALLY RELATED LIPIDS AS VANILLOID RECEPTOR MODULATORS FORSKARPATENT I SYD AB (SE) 2001-11-15 WO disclosed
EP-1084098-A1 INHIBITORS OF THE ANANDAMIDE TRANSPORTER AS ANALGESIC AGENTS Makriyannis, Alexandros (US) 2001-03-21 EP disclosed
WO-1999064389-A1 INHIBITORS OF THE ANANDAMIDE TRANSPORTER AS ANALGESIC AGENTS MAKRIYANNIS ALEXANDROS (US) 1999-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252865-A1 CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS ACHE, CHRNA10, CHRNA5 CNR1 7/4885ALDH1A1 818/4885CNR2 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.