Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL3843204 | 0.88 | POLB (0.83) | POLBMAPTSMN1; SMN2P2RX7HTT | |
| SCHEMBL3824098 | 0.84 | POLB (0.66) | POLBMAPTP2RX7L3MBTL1ALDH1A1 | |
| SCHEMBL3821889 | 0.83 | BRD4 (0.51) | POLBMAPTSMN1; SMN2HTTKMT2A | |
| SCHEMBL688492 | 0.82 | POLB (1.00) | POLBMAPTSMN1; SMN2P2RX7HTT | |
| SCHEMBL12145251 | 0.80 | POLB (0.68) | POLBMAPTP2RX7L3MBTL1ALDH1A1 | |
| SCHEMBL29265031 | 0.79 | POLB (0.67) | POLBMAPTSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3843203 | 0.79 | POLB (0.59) | POLBP2RX7L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL15042019 | 0.79 | POLB (0.66) | POLBP2RX7L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL3829072 | 0.78 | DGKA (0.47) | POLBSMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| Triethylene Glycol SCHEMBL1360705 | 0.77 | POLB (0.76) | POLBMAPTSMN1; SMN2P2RX7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |