Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
| ▸ | ME3 | Q16798 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827091 | 0.91 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4ETSHRCHRM5 | |
| SCHEMBL3860025 | 0.91 | L3MBTL1 (0.53) | L3MBTL1RAB9AALDH1A1KDM4ETSHR | |
| SCHEMBL3830922 | 0.90 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1KDM4ETSHRCHRM5 | |
| SCHEMBL3830332 | 0.88 | MEN1 (0.45) | L3MBTL1RAB9AALDH1A1KDM4ETSHR | |
| SCHEMBL4733653 | 0.87 | MAPT (0.42) | L3MBTL1RAB9AALDH1A1KDM4ETSHR | |
| SCHEMBL3824125 | 0.86 | L3MBTL1 (0.44) | L3MBTL1RAB9AKDM4EOPRM1OPRK1 | |
| SCHEMBL4737954 | 0.86 | KDM4E (0.45) | L3MBTL1ALDH1A1KDM4ETSHRCHRM5 | |
| SCHEMBL3823072 | 0.84 | KDM4E (0.45) | L3MBTL1RAB9AKDM4EOPRM1OPRK1 | |
| SCHEMBL4735130 | 0.84 | KMT2A (0.45) | RAB9AALDH1A1KDM4ETSHROPRM1 | |
| SCHEMBL4735586 | 0.84 | LMNA (0.53) | L3MBTL1ALDH1A1KDM4ETSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |