Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860025 | 0.89 | L3MBTL1 (0.53) | KDM4ELMNAL3MBTL1RAB9ADRD2 | |
| SCHEMBL3824125 | 0.89 | L3MBTL1 (0.44) | KDM4EL3MBTL1RAB9ADRD2DRD1 | |
| SCHEMBL3823112 | 0.89 | RAB9A (0.52) | SMN1; SMN2L3MBTL1RAB9ADRD2DRD1 | |
| SCHEMBL8185382 | 0.87 | RAB9A (0.48) | SMN1; SMN2L3MBTL1RAB9ADRD2DRD1 | |
| SCHEMBL3827371 | 0.85 | KDM4E (0.44) | KDM4ELMNAL3MBTL1RAB9ADRD2 | |
| SCHEMBL8184147 | 0.85 | L3MBTL1 (0.47) | KDM4ESMN1; SMN2L3MBTL1RAB9ADRD2 | |
| SCHEMBL3858086 | 0.85 | QPCT (0.43) | LMNADRD2DRD1DRD5DRD3 | |
| SCHEMBL8195090 | 0.84 | L3MBTL1 (0.40) | LMNAL3MBTL1DRD2DRD1DRD5 | |
| SCHEMBL3823632 | 0.84 | L3MBTL1 (0.45) | KDM4EL3MBTL1RAB9ADRD2DRD1 | |
| SCHEMBL3830922 | 0.84 | L3MBTL1 (0.43) | KDM4ELMNASMN1; SMN2L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |