SCHEMBL382367

SCHEMBL382367

C1=CC2(Oc3ccccc31)c1ccccc1Oc1ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
MAPT P10636 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NPSR1 Q6W5P4 3/20 0.35
HTT P42858 1/20 0.35
GAA P10253 2/20 0.33
TP53 P04637 2/20 0.33
LMNA P02545 1/20 0.33
ALPG P10696 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALOX5 P09917 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TRPA1 O75762 1/20 0.32
ADRA1D P25100 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30697691 1.00 HTR2C (0.44) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8862470 0.82 HTR2C (0.45) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8862518 0.78 MAPT (0.40) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8680760 0.78 MEN1 (0.50) MAPTMEN1KMT2AALDH1A1NPSR1
SCHEMBL29592742 0.78 MEN1 (0.33) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL8871056 0.77 HTR2C (0.46) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8680106 0.74 MAPT (0.39) MAPTMEN1KMT2AALDH1A1HTT
SCHEMBL8681103 0.73 KDM4E (0.50) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL381889 0.71 HTR2C (0.52) HTR2CHTR2BMAPTMEN1KMT2A
SCHEMBL8887017 0.69 MAPT (0.33) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6551710-B1 Primer composition comprises dithiol or polythiol compound and allyl or vinyl monomer; coating composition can further comprise photochromic dyes and additional polymerizable monomers; coatings for lenses SOLA INTERNATIONAL HOLDINGS, LTD. (AU) 2003-04-22 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
WO-1997027223-A1 PROCESS FOR PREPARING OPTICAL ARTICLES SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1997-07-31 WO claimed
US-12600879-B2 Coated lens and method for manufacturing the same CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2026-04-14 US disclosed
EP-4493966-A2 COATED LENS AND METHOD FOR MANUFACTURING THE SAME Carl Zeiss Vision International GmbH (DE) 2025-01-22 EP disclosed
US-20240417588-A1 COATED LENS AND METHOD FOR MANUFACTURING THE SAME CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2024-12-19 US disclosed
EP-3488287-B1 PRINTING INK, PREFERABLY 3D PRINTING INK, SPECTACLE LENS, AND METHOD FOR MANUFACTURING AN EYEGLASS LENS ZEISS CARL VISION INT GMBH (DE) 2023-12-20 EP disclosed
WO-2023175193-A2 COATED LENS AND METHOD FOR MANUFACTURING THE SAME CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2023-09-21 WO disclosed
US-11754860-B2 Photochromic lens with laminated film, method for producing a photochromic lens, and a spectacle frame CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2023-09-12 US disclosed
US-20210156739-A1 Wearable UV Exposure Sensor BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2021-05-27 US disclosed
US-20200201079-A1 PHOTOCHROMIC LENS WITH LAMINATED FILM, METHOD FOR PRODUCING A PHOTOCHROMIC LENS, AND A SPECTACLE FRAME CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2020-06-25 US disclosed
EP-0822948-A1 TINTABLE CROSS-LINKABLE COMPOSITIONS SOLA INTERNATIONAL HOLDINGS, LTD. (AU) 1998-02-11 EP disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
EP-0797786-A1 INCORPORATING PHOTOCHROMIC MOLECULES IN LIGHT TRANSMISSIBLE ARTICLES SOLA INTERNATIONAL HOLDINGS, LTD. (AU) 1997-10-01 EP disclosed
WO-1997027223-A1 PROCESS FOR PREPARING OPTICAL ARTICLES SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1997-07-31 WO disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
WO-1996034025-A1 TINTABLE CROSS-LINKABLE COMPOSITIONS SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1996-10-31 WO disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
WO-1996018928-A1 INCORPORATING PHOTOCHROMIC MOLECULES IN LIGHT TRANSMISSIBLE ARTICLES SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1996-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600879-B2 Coated lens and method for manufacturing the same GMFG, AQP4, METTL14 HTR2C 2276/4885HTR2B 3892/4885MAPT 1192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.