Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682312 | 0.75 | ALDH1A1 (0.37) | MAPTTP53HSD17B10HPGDKDM4E | |
| SCHEMBL24602910 | 0.73 | CA12 (0.43) | CA12CA1CA9CYP3A4 | |
| SCHEMBL8870392 | 0.73 | ALDH1A1 (0.35) | MAPTTP53HSD17B10HPGDKDM4E | |
| SCHEMBL15989633 | 0.73 | ALDH1A1 (0.56) | MAPTTP53HSD17B10HPGDKDM4E | |
| SCHEMBL2126375 | 0.72 | ALDH1A1 (0.54) | MAPTHSD17B10HPGDKDM4ENPC1 | |
| SCHEMBL382367 | 0.69 | HTR2C (0.44) | MAPTTP53HSD17B10KDM4EALDH1A1 | |
| SCHEMBL30697691 | 0.69 | HTR2C (0.44) | MAPTTP53HSD17B10KDM4EALDH1A1 | |
| SCHEMBL9351287 | 0.67 | MAPT (0.37) | MAPTTP53HSD17B10HPGDKDM4E | |
| SCHEMBL8680100 | 0.66 | MAPT (0.70) | MAPTTP53HSD17B10HPGDKDM4E | |
| SCHEMBL20848050 | 0.66 | KDM4E (0.40) | MAPTHPGDKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5645768-A | PYRAN IN WHICH AROMATIC RESIDUES ARE RIGIDLY ATTACHED TO A SPIROPYRAN; TINTING OPTICAL PLASTIC MATERIAL | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-07-08 | — | — | US | disclosed |