Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.73 |
| ▸ | MITF | O75030 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.68 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.66 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.66 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.66 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415838 | 1.00 | PTPN1 (0.73) | PTPN1MITFNPC1RAB9AENPP1 | |
| Hydrochloric Acid SCHEMBL5794613 | 0.98 | PTPN1 (0.71) | PTPN1MITFNPC1RAB9AENPP1 | |
| SCHEMBL17342684 | 0.91 | ENPP1 (0.70) | PTPN1MITFNPC1RAB9AENPP1 | |
| SCHEMBL9767723 | 0.90 | NPC1 (0.76) | PTPN1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL10684470 | 0.90 | PTPN1 (0.88) | PTPN1MITFNPC1RAB9AKCNQ3 | |
| SCHEMBL611657 | 0.90 | NPC1 (0.76) | PTPN1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL10939703 | 0.90 | NPC1 (0.76) | PTPN1NPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL5946767 | 0.85 | PTPN1 (0.73) | PTPN1MITFNPC1RAB9AKCNQ3 | |
| SCHEMBL8768807 | 0.85 | MEN1 (0.86) | PTPN1MITFNPC1RAB9AKCNQ3 | |
| SCHEMBL8770854 | 0.85 | PTPN1 (0.79) | PTPN1MITFNPC1RAB9AKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |