Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.86 |
| ▸ | POLB | P06746 | 2/20 | 0.86 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.79 |
| ▸ | MITF | O75030 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | SNCA | P37840 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.61 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.60 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.60 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.60 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | NOS1 | P29475 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684470 | 0.94 | PTPN1 (0.88) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL21254869 | 0.91 | MEN1 (0.73) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL8770854 | 0.88 | PTPN1 (0.79) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL4635501 | 0.86 | MITF (1.00) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL2415708 | 0.86 | PTPN1 (0.76) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL3639776 | 0.86 | MITF (1.00) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL4491689 | 0.86 | PTPN1 (0.76) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL3823913 | 0.85 | PTPN1 (0.73) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL16741759 | 0.85 | MEN1 (0.81) | MEN1KMT2APOLBPTPN1MITF | |
| SCHEMBL10192214 | 0.85 | RAB9A (0.81) | MEN1KMT2APOLBPTPN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-B1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARM INC (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20180163061-A1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180163061-A1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| EP-3309851-A1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT | Nissan Chemical Industries, Ltd. (JP) | 2018-04-18 | — | — | EP | disclosed |
| US-9622991-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9144557-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2015-09-29 | — | — | US | disclosed |
| US-20150252043-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2015-09-10 | — | — | US | disclosed |
| US-20140243324-A1 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2014-08-28 | — | — | US | disclosed |
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243324-A1 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | HGF, EPOR, MPL | MEN1 1370/4885KMT2A 2225/4885POLB 3018/4885 |
| US-20150252043-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | MEN1 1395/4885KMT2A 806/4885POLB 3224/4885 |
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | MEN1 1395/4885KMT2A 806/4885POLB 3224/4885 |
| US-20180163061-A1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLCO4C1, SLCO2A1, SLC26A3 | MEN1 2089/4885KMT2A 1997/4885POLB 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.