Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822613 | 0.81 | MCOLN3 (0.60) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL10968043 | 0.79 | ALDH1A1 (0.55) | LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5808143 | 0.79 | MCOLN3 (0.58) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL4758890 | 0.79 | MCOLN3 (0.58) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL6534930 | 0.79 | MCOLN3 (0.58) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL6535002 | 0.79 | MCOLN3 (0.78) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL9355856 | 0.79 | MCOLN3 (0.58) | MCOLN3KDM4ECA12CA9PGR | |
| Hydrochloric Acid SCHEMBL5805301 | 0.78 | MCOLN3 (0.57) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL3853249 | 0.78 | MCOLN3 (0.57) | MCOLN3KDM4ECA12CA9PGR | |
| SCHEMBL3826485 | 0.78 | MCOLN3 (0.57) | MCOLN3KDM4ECA12CA9PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129365-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | WO | claimed |