Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | FES | P07332 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106699 | 0.83 | LOX (0.47) | ALDH1A1HTTSMN1; SMN2HSD11B1LMNA | |
| SCHEMBL7234031 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBLMNA | |
| SCHEMBL3649736 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBLMNA | |
| SCHEMBL27560438 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBLMNA | |
| SCHEMBL29978694 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBLMNA | |
| SCHEMBL3823916 | 0.79 | MCOLN3 (0.60) | HTTSMN1; SMN2LMNA | |
| SCHEMBL701463 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2POLBHSD11B1 | |
| SCHEMBL23057072 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBLMNA | |
| SCHEMBL2229460 | 0.76 | PGR (0.54) | ALDH1A1HTTSMN1; SMN2POLBHSD11B1 | |
| SCHEMBL8074308 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154969-A2 | Piperazine derivatives and their acid addition salts | MITSUBISHI KASEI CORPORATION (JP) | 1985-09-18 | — | — | EP | disclosed |