Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306541 | 0.83 | ALOX5AP (0.57) | ALOX5APFEN1KMT2AMEN1HTT | |
| SCHEMBL6535002 | 0.80 | MCOLN3 (0.78) | MCOLN3KDM4EPGRCA12CA9 | |
| SCHEMBL15924549 | 0.80 | ALOX5AP (0.44) | ALOX5APFEN1KMT2AMEN1PTGS2 | |
| SCHEMBL6904423 | 0.80 | OPRM1 (0.58) | ALOX5APFEN1KMT2AMEN1PTGS2 | |
| SCHEMBL6698432 | 0.80 | ALOX5AP (0.58) | ALOX5APFEN1KMT2AMEN1HTT | |
| SCHEMBL10782653 | 0.80 | ALOX5AP (0.44) | CA12CA9ALOX5APFEN1KMT2A | |
| SCHEMBL3823916 | 0.78 | MCOLN3 (0.60) | MCOLN3KDM4EPGRCA12CA9 | |
| SCHEMBL3822613 | 0.78 | MCOLN3 (0.60) | MCOLN3KDM4EPGRCA12CA9 | |
| SCHEMBL10957993 | 0.77 | SMN1; SMN2 (0.46) | KDM4EALOX5APFEN1KMT2AMEN1 | |
| SCHEMBL6534930 | 0.76 | MCOLN3 (0.58) | MCOLN3KDM4EPGRCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641472-B | Recording material and recording sheet | 日本曹达株式会社 | 2021-07-27 | — | — | CN | disclosed |
| EP-2104677-A1 | SPIROPIPERIDINE GLYCINAMIDE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008084005-A1 | SPIROPIPERIDINE GLYCINAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-17 | — | — | WO | disclosed |