Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17703180 | 0.77 | TYR (0.65) | TYRGAA | |
| SCHEMBL11865275 | 0.77 | TYR (0.65) | TYRGAA | |
| SCHEMBL8365957 | 0.74 | TYR (0.49) | CA1CA2CA9CA12CA14 | |
| SCHEMBL7012899 | 0.74 | CHRM1 (0.55) | SMN1; SMN2ALDH1A1HPGDTYRLMNA | |
| SCHEMBL28220955 | 0.74 | TYR (0.43) | TSHRALDH1A1HSD17B10HPGDTYR | |
| SCHEMBL984999 | 0.72 | MAPT (0.50) | CA1CA2CA9CA12CA14 | |
| SCHEMBL29405346 | 0.72 | MAPT (0.50) | CA1CA2CA9CA12CA14 | |
| Diphenylmethanol SCHEMBL28302196 | 0.71 | CA12 (0.57) | CA1CA2CA9CA12CA14 | |
| SCHEMBL21726592 | 0.71 | ALDH1A1 (0.53) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12799419 | 0.70 | MEN1 (0.46) | TSHRSMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | claimed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | claimed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | claimed |
| EP-2010294-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | claimed |
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
| EP-2010294-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | CA1 2560/4885CA2 1809/4885CA9 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.